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HRID712834

反应详情

EQUATION

反应方程式

HRID 712834 的结构方程式

REACTANTS

反应物

3
结构：O=C([O-])[O-].[Na+].[Na+]
HCID10340

Carbonic acid sodium salt (1:2)

CNa2O3

结构：FC(F)(F)c1ccc(CBr)cc1
HCID123062

1-(Bromomethyl)-4-(trifluoromethyl)benzene

C8H6BrF3

结构：COC(=O)[C@@]1(C)CCCN1.Cl
HCID71306205

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)[C@@]1(C)CCCN1Cc1ccc(C(F)(F)F)cc1
HCID71204723

未命名化合物

PROCEDURE

实验过程

The title compound (D80) (50 mg) was prepared according to the general procedure for substituted benzyl amines preparation starting from (R)-methyl 2-methylpyrrolidine-2-carboxylate hydrochloride (D50) (60 mg) and 4-(Trifluoromethyl)benzyl bromide (0.126 ml). (Na2CO3: 4 eq; reaction time 18 hrs; 68° C.)