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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 712858Generated: November 3, 2026

Lithium Hydroxide → HCID 131733992, compound

https://huagongshe.com/reaction/712858

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantHCID 71204723HCID 71204723—
ProductHCID 131733992HCID 131733992—

Reaction Steps

The title compound (D113) (42 mg) was prepared according to the general procedure for esters hydrolysis (Method A) starting from (R)-methyl 2-methyl-1-(4-(trifluoromethyl)benzyl)pyrrolidine-2-carboxylate (D80) (50 mg). (LiOH: 3 eq; Reaction time: 18 hrs; RT)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181279B2
Source datasetuspto-grants-2015_11
ORD IDord-1aa536e840fd4343abee18f2c12c5f4d
Source noteuspto-grants-2015_11