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HRID712858

反应详情

EQUATION

反应方程式

HRID 712858 的结构方程式

REACTANTS

反应物

2
结构：[Li+].[OH-]
HCID3939

Lithium hydroxide anhydrous

HLiO

结构：COC(=O)[C@@]1(C)CCCN1Cc1ccc(C(F)(F)F)cc1
HCID71204723

未命名化合物

PRODUCTS

生成物

1
结构：C[C@]1(C(=O)[O-])CCCN1Cc1ccc(C(F)(F)F)cc1.[Li+]
HCID131733992

未命名化合物

PROCEDURE

实验过程

The title compound (D113) (42 mg) was prepared according to the general procedure for esters hydrolysis (Method A) starting from (R)-methyl 2-methyl-1-(4-(trifluoromethyl)benzyl)pyrrolidine-2-carboxylate (D80) (50 mg). (LiOH: 3 eq; Reaction time: 18 hrs; RT)