HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 71204729, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 1-(Bromomethyl)-4-(trifluoromethyl)benzene | HCID 123062 | — |
| Reactant | HCID 71204683 | HCID 71204683 | — |
| Product | HCID 71204729 | HCID 71204729 | — |
Reaction Steps
The title compound (D118) (24 mg) was prepared according to the general procedure for substituted benzyl amines preparation starting from methyl 4-((S)-1-((R)-piperidine-2-carboxamido)ethyl)benzoate (D86) (40 mg) and 4-(trifluoromethyl)benzylbromide (0.032 ml). (Na2CO3: 2.5 eq; reaction time: 4 hrs; 60° C.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-955a4ecdc528406a9c0722eab4f3438f |
| Source note | uspto-grants-2015_11 |