HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-(1-aminocyclopropyl)benzoate hydrochloride → HCID 71186634, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-(1-aminocyclopropyl)benzoate hydrochloride | HCID 66824369 | — |
| Reactant | HCID 71186564 | HCID 71186564 | — |
| Product | HCID 71186634 | HCID 71186634 | 34.3% |
Reaction Steps
The title compound (D156) (12 mg) was prepared according to the general procedure for amides preparation (Method C) starting from 2-(4-(trifluoromethyl)benzyl)-2-azabicyclo[2.2.2]octane-3-carboxylic acid (D111) (22.5 mg) and methyl 4-(1-aminocyclopropyl)benzoate hydrochloride (18 mg). (Reaction time: 2 hrs; 60° C.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-f10e65ffe7f147fb855f45bafe8e7612 |
| Source note | uspto-grants-2015_11 |