HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride → HCID 71204713, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride | HCID 57462942 | — |
| Reactant | HCID 131733994 | HCID 131733994 | — |
| Product | HCID 71204713 | HCID 71204713 | 48.6% |
Reaction Steps
The title compound (D164) (37 mg) was prepared according to the general procedure for amides preparation (Method A) starting from lithium (R)-4,4-difluoro-1-(3-(trifluoromethyl)benzyl)pyrrolidine-2-carboxylate (D115) (51 mg) and (S)-methyl 4-(1-aminoethyl)benzoate hydrochloride (35 mg). (Reaction time: 48 hrs; RT).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-cb1d23f8d77c4b9e94c3dea3b453d7d3 |
| Source note | uspto-grants-2015_11 |