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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 712899Generated: October 30, 2026

Lithium Hydroxide → HCID 71186520, compound

https://huagongshe.com/reaction/712899

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
ReactantHCID 71186482HCID 71186482—
ProductHCID 71186520HCID 7118652076.7%

Reaction Steps

The title compound (E8) (35 mg) was prepared according to the general procedure for esters hydrolysis (Method D) starting from methyl 4-(1-(6-((6-(trifluoromethyl)pyridin-3-yl)methyl)-6-azaspiro[2.5]octane-5-carboxamido)cyclopropyl)benzoate (D124) (47 mg). (LiOH: 4 eq; Reaction time: 5 hrs; RT)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181279B2
Source datasetuspto-grants-2015_11
ORD IDord-cc878bbf69a943a09b53e733043d8296
Source noteuspto-grants-2015_11