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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 712900Generated: October 29, 2026

Lithium hydroxide, monohydrate → HCID 71186491, compound

https://huagongshe.com/reaction/712900

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium hydroxide, monohydrateHCID 168937—
ReactantHCID 71186223HCID 71186223—
ProductHCID 71186491HCID 7118649166.2%

Reaction Steps

The title compound (E9) (39 mg) was prepared according to the general procedure for esters hydrolysis (Method D) starting from methyl 4-(1-(6-(3-(trifluoromethyl)benzyl)-6-azaspiro[2.5]octane-5-carboxamido)cyclopropyl)benzoate (single unknown enantiomer) (D125) (60.7 mg). (LiOH H2O: 4 eq; reaction time: 18 hrs)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181279B2
Source datasetuspto-grants-2015_11
ORD IDord-8e8d17651c794028ab33783fb100a383
Source noteuspto-grants-2015_11