HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium hydroxide, monohydrate → HCID 71186331, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium hydroxide, monohydrate | HCID 168937 | — |
| Reactant | HCID 71186580 | HCID 71186580 | — |
| Product | HCID 71186331 | HCID 71186331 | 24.4% |
Reaction Steps
The title compound (E11) (4.5 mg) was prepared according to the general procedure for esters hydrolysis (Method B) starting from methyl 4-((1S)-1-(5-methyl-6-(4-(trifluoromethyl)benzyl)-6-azaspiro[2.5]octane-5-carboxamido)ethyl)benzoate (D130) (19 mg). (LiOH H2O: 4 eq; reaction time: 18 hrs)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-7b12062bf90a4a90aa1e97acc07c926f |
| Source note | uspto-grants-2015_11 |