反应详情

The title compound (E11) (4.5 mg) was prepared according to the general procedure for esters hydrolysis (Method B) starting from methyl 4-((1S)-1-(5-methyl-6-(4-(trifluoromethyl)benzyl)-6-azaspiro[2.5]octane-5-carboxamido)ethyl)benzoate (D130) (19 mg). (LiOH H2O: 4 eq; reaction time: 18 hrs)