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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 712903Generated: October 29, 2026

Lithium hydroxide, monohydrate → HCID 71186208, compound

https://huagongshe.com/reaction/712903

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium hydroxide, monohydrateHCID 168937—
ReactantHCID 71186492HCID 71186492—
ProductHCID 71186208HCID 7118620864.5%

Reaction Steps

The title compound (E12) (88.4 mg) was prepared according to the general procedure for esters hydrolysis (Method C) starting from methyl 4-(1-(4,4-dimethyl-1-(4-(trifluoromethyl)benzyl)piperidine-2-carboxamido)cyclopropyl)benzoate (enantiomer 2) (D131 b) (141 mg). (LiOH H2O: 4 eq; reaction time: 18 hrs)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181279B2
Source datasetuspto-grants-2015_11
ORD IDord-dc82b365163947c4ae4ef58812446a1a
Source noteuspto-grants-2015_11