HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium hydroxide, monohydrate → HCID 71204694, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium hydroxide, monohydrate | HCID 168937 | — |
| Reactant | HCID 71204702 | HCID 71204702 | — |
| Product | HCID 71204694 | HCID 71204694 | 65.1% |
Reaction Steps
The title compound (E15) (15.8 mg) was prepared according to the general procedure for esters hydrolysis (Method D) starting from methyl 4-(1-((2R)-4-fluoro-1-(4-(trifluoromethyl)benzyl)piperidine-2-carboxamido)cyclopropyl)benzoate (D134) (25 mg). (LiOH H2O: 4 eq; reaction time: 5 hrs)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-5af9e533bfcf44109d961b8a22ec0e1d |
| Source note | uspto-grants-2015_11 |