HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium hydroxide, monohydrate → HCID 71204738, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium hydroxide, monohydrate | HCID 168937 | — |
| Reactant | HCID 71204732 | HCID 71204732 | — |
| Product | HCID 71204738 | HCID 71204738 | 74.3% |
Reaction Steps
The title compound (E26) (7.2 mg) was prepared according to the general procedure for esters hydrolysis (Method D) starting from methyl 4-((1S)-1-((3R)-2-(4-(trifluoromethyl)benzyl)-2-azabicyclo[4.1.0]heptane-3-carboxamido)ethyl)benzoate (diastereoisomers mixture) (D143) (10 mg). (LiOH H2O: 4 eq; reaction time: 10 hrs)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-9c0f5d59f49a4c46957aa1cd5d9cf5ff |
| Source note | uspto-grants-2015_11 |