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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 712916Generated: October 31, 2026

Lithium hydroxide, monohydrate → HCID 71204676, compound

https://huagongshe.com/reaction/712916

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium hydroxide, monohydrateHCID 168937—
ReactantHCID 117966734HCID 117966734—
ProductHCID 71204676HCID 7120467647.5%

Reaction Steps

The title compound (E31) (46 mg) was prepared according to the general procedure for esters hydrolysis (Method C) starting from methyl 4-(1-((3R)-2-(4-(trifluoromethyl)benzyl)-2-azabicyclo[3.1.0]hexane-3-carboxamido)cyclopropyl)benzoate (diastereoisomer 2) (D148) (100 mg). (LiOH H2O: 4 eq; reaction time: 18 hrs)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181279B2
Source datasetuspto-grants-2015_11
ORD IDord-019baa74392e45d1848f0261509ff564
Source noteuspto-grants-2015_11