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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 712920Generated: October 30, 2026

Lithium hydroxide, monohydrate → HCID 71186598, compound

https://huagongshe.com/reaction/712920

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium hydroxide, monohydrateHCID 168937—
ReactantHCID 71186323HCID 71186323—
ProductHCID 71186598HCID 7118659829.6%

Reaction Steps

The title compound (E36) (2 mg) was prepared according to the general procedure for esters hydrolysis (Method C) starting from methyl 4-((1S)-1-(1-(4-(trifluoromethyl)benzyl)azetidine-2-carboxamido)ethyl)benzoate (diastereoisomer 2) (D152b) (7 mg). (LiOH H2O: 4 eq; reaction time: 18 hrs)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09181279B2
Source datasetuspto-grants-2015_11
ORD IDord-f7dbc893c2e047ce8d63b236ca22ec58
Source noteuspto-grants-2015_11