HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium hydroxide, monohydrate → HCID 117966823, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium hydroxide, monohydrate | HCID 168937 | — |
| Reactant | HCID 71204695 | HCID 71204695 | — |
| Product | HCID 117966823 | HCID 117966823 | 80.4% |
Reaction Steps
The title compound (E41) (3.9 mg) was prepared according to the general procedure for esters hydrolysis (Method C) starting from (R)-methyl 4-(1-(2-methyl-1-(4-(trifluoromethyl)benzyl)piperidine-2-carboxamido)cyclopropyl)benzoate (D157) (5 mg). (LiOH H2O: 4 eq; reaction time: 18 hrs).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-c02771017fe64673bffce54a12c6a5cd |
| Source note | uspto-grants-2015_11 |