HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium hydroxide, monohydrate → HCID 71186440, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium hydroxide, monohydrate | HCID 168937 | — |
| Reactant | HCID 117966817 | HCID 117966817 | — |
| Product | HCID 71186440 | HCID 71186440 | 88.9% |
Reaction Steps
The title compound (E43) (11.2 mg) was prepared according to the general procedure for esters hydrolysis (Method D) starting from (R)-methyl 4-(1-(2-methyl-1-(4-(trifluoromethyl)benzyl)pyrrolidine-2-carboxamido)cyclopropyl)benzoate (D159) (13 mg). (LiOH H2O: 4 eq; reaction time: 18 hrs).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09181279B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-98760c02dfd64065a9c821fae1a732a1 |
| Source note | uspto-grants-2015_11 |