Hydrogen Peroxide → HCID 66769729, compound

HRID 713167Notes

Reaction equation

HRID 713167 reaction equation
[Br:1][CH2:2][CH2:3][CH2:4][P:5]([C:17]([C:19]1[C:24]([CH3:25])=[CH:23][C:22]([CH3:26])=[CH:21][C:20]=1[CH3:27])=[O:18])[C:6]([C:8]1[C:13]([CH3:14])=[CH:12][C:11]([CH3:15])=[CH:10][C:9]=1[CH3:16])=[O:7].OO.C([O:32]CC)C>C1(C)C=CC=CC=1>[Br:1][CH2:2][CH2:3][CH2:4][P:5]([C:6]([C:8]1[C:13]([CH3:14])=[CH:12][C:11]([CH3:15])=[CH:10][C:9]=1[CH3:16])=[O:7])([C:17]([C:19]1[C:20]([CH3:27])=[CH:21][C:22]([CH3:26])=[CH:23][C:24]=1[CH3:25])=[O:18])=[O:32]

Participants

5

Reactant 3

HCID 784Hydrogen PeroxideHCID 3283Diethyl EtherHCID 66769719HCID 66769719, compound

Product 1

HCID 66769729HCID 66769729, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Conditions

Temperature
40 °C

Procedure

((3-bromopropyl)phosphinediyl)bis(mesitylmethanone) of example 4 (1.16 g, 2.59 mmol, 1 eq.) was dissolved in toluene (5 mL) and hydrogen peroxide (10%) (8.88 mL, 2.59 mmol, 1 eq.) was added. The reaction mixture was stirred at 40° C. for 12 hours. Afterwards diethylether (50 mL) were added and the solution was washed with twice sodium hydrogencarbonate (2%) solution, once with brine and finally dried with magnesium sulfate. After removing the solvent in vacuo at room temperature, the pure product was obtained as a yellow oil (Yield: 0.97 g, 2.10 mmol).

Workup

  1. washthe solution was washed with twice sodium hydrogencarbonate (2%) solution, once with brine
  2. dry with materialfinally dried with magnesium sulfate
  3. customAfter removing the solvent in vacuo at room temperature

Sources & evidence

ORD record
ord-a5b6fbbad8fc455eb3ac0a074a42ca93
Source dataset
uspto-grants-2015_11
Patent number
US09181358B2

Reaction notes

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