反应详情

To a solution of tert-butyl (4-oxo-4,5,7,8-tetrahydro-3H-pyrano[4,3-d]pyrimidin-2-yl)methyl(thiophen-2-ylmethyl)carbamate (0.87 g, 2.3 mmol) in methanol (5 mL) was added hydrochloride acid (2.3 mL, 4M in dioxane). The mixture was stirred at ambient temperature for 24 h, filtered and washed with ether to give the title compound as a white solid (710 mg, 98% yield).

1. filtrationfiltered
2. washwashed with ether