反应详情

A stirred solution of ethyl 5-methoxy-1-oxo-1,3-dihydrospiro[indene-2,4′-piperidine]-1′-carboxylate (590 mg, 1.95 mmol) in HCl (6.5 mL, 38.9 mmol) was heated at 100° C. overnight. The reaction mixture was concentrated to dryness to give the title compound (511 mg, 2.21 mmol) without any additional purification. MS calculated for C14H17NO2 232.3. found (ESI) m/z 232.4 (M+H)+, retention time 0.90 min.

1. concentrationThe reaction mixture was concentrated to dryness