Toluene → HCID 58225146, compound

HRID 713550Notes

Reaction equation

HRID 713550 reaction equation
[CH2:1]1[C:4]2[CH:5]=C[C:7](C(C3C=CC=CC=3)(C3C=CC=CC=3)O)=[CH:8][C:3]=2[CH2:2]1.[C:23]([Cl:26])(=O)[CH3:24].[C:27]1(C)[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[Cl:26][C:23]([C:27]1[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=1)([C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)[C:24]1[CH:7]=[CH:8][C:3]2[CH2:2][CH2:1][C:4]=2[CH:5]=1

Participants

4

Reactant 3

HCID 1140TolueneHCID 6367Acetyl chlorideHCID 58225130HCID 58225130, compound

Product 1

HCID 58225146HCID 58225146, compound

Procedure

(1,2-dihydrocyclobutabenzen-4-yl)diphenylmethanol (0.8 g, 2.8 mmol) and acetylchloride (20 ml, 280 mmol) was refluxed in 30 mL of toluene for 2 hours. The solvent was then evaporated under reduced pressure. The residue was used for the next step without purification. 0.8 g of the product was obtained.

Workup

  1. customThe solvent was then evaporated under reduced pressure
  2. customThe residue was used for the next step without purification

Sources & evidence

ORD record
ord-73f3bbb39331443bb1423d0afd61d086
Source dataset
uspto-grants-2015_11
Patent number
US09184394B2

Reaction notes

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