反应详情

After dripping 1M phenylmagnesium bromide (20 ml, 20.0 mmol) into the starting material 10-phenyl-1H-indeno[1,2-b]quinolin-11-one (3.07 g, 10.0 mmol) which is dissolved in pure tetrahydrofuran, the mixed solution undergoes reaction for 24 hours at room temperature. Then, the reaction is terminated by adding ammonium chloride solution therein. Finally, 3.47 g of 10,11-diphenyl-11H-indeno[1,2-b]quinolin-11-ol is obtained by filtering the mixed solution to remove precipitates. The percentage yield is 90.0%. 10-diphenyl-11H-indeno[1,2-b]quinolin-11-ol obtained here can be also used as starting materials to produce other 6H-indeno[2,1-b]quinoline derivatives.

1. customreaction for 24 hours at room temperature
2. customThen, the reaction is terminated
3. additionby adding ammonium chloride solution