HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → N-methyl-3-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | 3-(Methylsulfamoyl)benzoic acid | HCID 252654 | — |
| Reactant | N-Hydroxynicotinimidamide | HCID 308113 | — |
| Product | N-methyl-3-(3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl)benzenesulfonamide | HCID 67025998 | — |
Reaction Steps
The title compound was prepared according to the procedure of Example 8 using N′-hydroxynicotinimidamide (Aldrich) and the product of Example 57A. 1H NMR (300 MHz, CD3OD) δ 2.60 (s, 3H), 7.65 (ddd, J=8.1, 5.0, 0.8 Hz, 1H), 7.87 (t, J=8.1 Hz, 1H), 8.15 (ddd, J=8.0, 1.9, 1.0 Hz, 1H), 8.48 (ddd, J=7.8, 1.7, 1.0 Hz, 1H), 8.58 (dt, J=8.1, 1.9 Hz, 1H), 8.67 (t, J=1.5 Hz, 1H), 8.75 (dd, J=4.7, 1.7 Hz, 1H), 9.31 (dd, J=2.2, 0.8 Hz, 1H) ppm; MS (DCl/NH3) m/z 317 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09186407B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-74599172ce5542a5a1e967a475fd7991 |
| Source note | uspto-grants-2015_11 |