反应详情

In analogy to the procedure described for the preparation of example 1, (rac)-N-(4-bromo-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide (intermediate A-1) was reacted with 3-chloro-4-fluorophenylboronic acid to give the title compound as light grey foam in 74% yield. MS: 333.1 (M+H+, 1Cl).