反应详情

In analogy to the procedure described for the preparation of intermediate A-4 [D], (+)-(R)-4-(2-fluoro-4-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydroisoquinolin-8-amine (example 74) and acetic acid gave the title compound as off-white amorphous solid in 90% yield. MS: 353.1 (M+H+).