反应详情

Following the procedure as described in Example 9, making variations as required to replace 1,2-diaminopropane with (S)-4-methylpentane-1,2-diamine to react with 2-benzamidoisonicotinic acid, N-(4-(4-isobutyl-4,5-dihydro-1H-imidazol-2-yl)pyridin-2-yl)benzamide was obtained in 23% yield: MS (ES+) m/z 323.2 (M+1).