HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propylenediamine → HCID 178441250, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propylenediamine | HCID 6567 | — |
| Reactant | (S)-4-methylpentane-1,2-diamine | HCID 10942394 | — |
| Reactant | 2-Benzamidoisonicotinic acid | HCID 64393851 | — |
| Product | HCID 178441250 | HCID 178441250 | 23% |
Reaction Steps
Following the procedure as described in Example 9, making variations as required to replace 1,2-diaminopropane with (S)-4-methylpentane-1,2-diamine to react with 2-benzamidoisonicotinic acid, N-(4-(4-isobutyl-4,5-dihydro-1H-imidazol-2-yl)pyridin-2-yl)benzamide was obtained in 23% yield: MS (ES+) m/z 323.2 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187426B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-72403330cb8b41178fb41baa31ea6fc3 |
| Source note | uspto-grants-2015_11 |