HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propylenediamine → HCID 178521775, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propylenediamine | HCID 6567 | — |
| Reactant | 3-(3,5-Difluorophenyl)propane-1,2-diamine | HCID 58247787 | — |
| Reactant | 2-Benzamidoisonicotinic acid | HCID 64393851 | — |
| Product | HCID 178521775 | HCID 178521775 | 24% |
Reaction Steps
Following the procedure as described in Example 9, making variations as required to replace 1,2-diaminopropane with 3-(3,5-difluorophenyl)propane-1,2-diamine to react with 2-benzamidoisonicotinic acid, N-(4-(4-(3,5-difluorobenzyl)-4,5-dihydro-1H-imidazol-2-yl)pyridin-2-yl)benzamide was obtained in 24% yield: MS (ES+) m/z 393.2 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187426B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-bce9c2773e8a43fc91ec8d35da525eb8 |
| Source note | uspto-grants-2015_11 |