Thionyl Chloride → 145883-50-7

HRID 714468Notes

Reaction equation

HRID 714468 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][CH:9]=1)[CH2:5]O.S(Cl)([Cl:12])=O>ClCCl>[ClH:12].[Cl:12][CH2:5][C:4]1[CH:3]=[C:2]([CH:9]=[CH:8][CH:7]=1)[NH2:1]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 802933-Aminobenzyl alcohol

Product 1

HCID 66630476145883-50-7

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

At 0° C., 2.0 g (16.24 mmol) of 3-aminobenzyl alcohol were initially charged in 60 ml of dichloromethane. 5.8 g (48.72 mmol) of thionyl chloride were added dropwise, and the reaction solution was stirred at RT overnight. The reaction solution was evaporated.

Workup

  1. customThe reaction solution was evaporated

Sources & evidence

ORD record
ord-d0c4d0c29c62452290d09987c625dc40
Source dataset
uspto-grants-2015_11
Patent number
US09187428B2

Reaction notes

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