4-Piperidinol, 1-methyl- → HCID 86694553, compound

HRID 714579Notes

Reaction equation

HRID 714579 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH:9][C:10]2[C:19]3[C:14](=[CH:15][C:16](F)=[C:17]([N+:20]([O-:22])=[O:21])[CH:18]=3)[N:13]=[CH:12][C:11]=2[C:24]#[N:25])[CH:5]=[CH:6][C:7]=1[F:8].[OH:26][CH:27]1[CH2:32][CH2:31][N:30]([CH3:33])[CH2:29][CH2:28]1>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:9][C:10]2[C:19]3[C:14](=[CH:15][C:16]([O:26][CH:27]4[CH2:32][CH2:31][N:30]([CH3:33])[CH2:29][CH2:28]4)=[C:17]([N+:20]([O-:22])=[O:21])[CH:18]=3)[N:13]=[CH:12][C:11]=2[C:24]#[N:25])[CH:5]=[CH:6][C:7]=1[F:8]

Participants

3

Reactant 2

HCID 660484-Piperidinol, 1-methyl-HCID 86694554HCID 86694554, compound

Product 1

HCID 86694553HCID 86694553, compound

Procedure

The compound was obtained according to the process of Preparation 2 with 4-(3-chloro-4-fluorophenylamino)-7-fluoro-6-nitroquinoline-3-carbonitrile and 4-hydroxy-1-methylpiperidine as starting materials.

Workup

  1. customThe compound was obtained

Sources & evidence

ORD record
ord-8f5a13e7548c4cac8b61d639278893f3
Source dataset
uspto-grants-2015_11
Patent number
US09187458B2

Reaction notes

Loading…