Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 714678Generated: October 30, 2026

5-(4-Chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one → HCID 86690916, compound

https://huagongshe.com/reaction/714678

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Chlorophenyl)-4-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-oneHCID 59536836—
ReactantHCID 67412369HCID 67412369—
ProductHCID 86690916HCID 86690916—

Reaction Steps

Analogously to the preparation of Example 18, 33 mg (0.11 mmol) of the compound from Example 5A were reacted with 35 mg (0.11 mmol) of the compound from Example 85A. This gave 16 mg (27% of theory) of the target compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09187466B2
Source datasetuspto-grants-2015_11
ORD IDord-f2461422d2ef4427810512284d124260
Source noteuspto-grants-2015_11