HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 89582530, compound → HCID 89579216, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 89582530 | HCID 89582530 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Platinum dioxide monohydrate | HCID 11139377 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 89579216 | HCID 89579216 | 93% |
Reaction Steps
(6-Methoxypyridazin-3-yl)pyrdin-3-ylmethanone (1.31 g, 6.1 mmol) were dissolved in ethanol (100 ml), platinum(IV) oxide hydrate (80% of Pt, 0.5 g, 2.2 mmol) was added, and the mixture was stirred with supply of hydrogen. Conventional work-up gave 1.26 g (93% yield) of (6-methoxypyridazin-3-yl)piperidin-3-ylmethanol as crude product, which was employed directly in the next step;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187469B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-a9e03142f9214e8cb9e99cb4896d3712 |
| Source note | uspto-grants-2015_11 |