反应详情

To a solution of (1-(4-nitro-1H-pyrazol-1-yl)cyclobutyl)methanol (480 mg) obtained in Step B of Example 127 in ethanol (30 mL) was added 10% palladium-carbon (100 mg), and the mixture was stirred at room temperature for 10 hr under hydrogen atmosphere (at normal pressures). The palladium-carbon was removed by filtration through Celite, and the solvent was evaporated under reduced pressure to give the title compound (400 mg).

1. customThe palladium-carbon was removed by filtration through Celite
2. customthe solvent was evaporated under reduced pressure