Hydrochloric Acid → HCID 117839929, compound

Participants

Reaction Steps

To tert-butyl 3-(4-((4-((3R)-3-cyano-3-ethyl-2-oxopyrrolidin-1-yl)pyrimidin-2-yl)amino)-1H-pyrazol-1-yl)azetidine-1-carboxylate (170 mg) obtained in Example 184 was added a solution of 4 M hydrogen chloride in ethyl acetate (6.0 mL), and the mixture was stirred at room temperature for 30 min. The solvent was evaporated under reduced pressure, and the residue was recrystallized (ethanol/ethyl acetate) to give the title compound (120 mg).

Provenance & Evidence