HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-ethyl-1H-pyrazole-3-carbaldehyde → HCID 68294498, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-ethyl-1H-pyrazole-3-carbaldehyde | HCID 7019415 | — |
| Reactant | 1-Methyl-1H-pyrazole-3-carboxaldehyde | HCID 7026090 | — |
| Reactant | 5-OXAZOLECARBOXALDEHYDE | HCID 11829372 | — |
| Reactant | HCID 178505943 | HCID 178505943 | — |
| Product | HCID 68294498 | HCID 68294498 | — |
| Product | HCID 117965526 | HCID 117965526 | — |
Reaction Steps
(4-Chloro-3-fluoro-phenyl)-(1-methyl-1H-pyrazol-3-yl)-methylamine (32a) was prepared analogously except oxazole-5-carbaldehyde was replaced with 1-methyl-1H-pyrazole-3-carbaldehyde (CASRN 27258-32-8) and (4-chloro-3-fluorophenyl)magnesium bromide was used in place of (3,4-dichlorophenyl)magnesium bromide in step 2. (4-Chloro-3-fluoro-phenyl)-(1-ethyl-1H-pyrazol-3-yl)-methylamine (32b) was prepared analogously except oxazole-5-carbaldehyde was replaced with 1-ethyl-1H-pyrazole-3-carbaldehyde (CASRN 942319-16-6).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187462B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-4cdeb1143bcb4dc8a28386fc7ee1c42c |
| Source note | uspto-grants-2015_11 |