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HRID71515

反应详情

EQUATION

反应方程式

HRID 71515 的结构方程式

REACTANTS

反应物

2
结构：CC(C)c1ccc(N)cc1
HCID7464

Cumidine

C9H13N

结构：Oc1cccc(Nc2nc(Cl)ncc2F)c1
HCID22060451

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)c1ccc(Nc2ncc(F)c(Nc3cccc(O)c3)n2)cc1
HCID22060781

未命名化合物

PROCEDURE

实验过程

In like manner to the preparation of N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(3-hydroxyphenyl)-2,4-pyrimidinediamine, the reaction of 2-chloro-5-fluoro-N4-(3-hydroxyphenyl)-4-pyrimidineamine with 4-isopropylaniline gave 5-fluoro-N4-(3-hydroxyphenyl)-N2-(4-isopropylphenyl)-2,4-pyrimidinediamine. LCMS: ret. time: 23.08 min.; purity: 99%; MS (m/e): 439 (MH+).

WORKUP

后处理

  1. customIn like manner to the preparation of N4-(3,4-ethylenedioxyphenyl)-5-fluoro-N2-(3-hydroxyphenyl)-2,4-pyrimidinediamine