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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 715227Generated: October 31, 2026

Methyl 3-(bromomethyl)-2-chloropyridine-4-carboxylate → HCID 89875005, compound

https://huagongshe.com/reaction/715227

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-(bromomethyl)-2-chloropyridine-4-carboxylateHCID 72213786—
ReactantHCID 89874548HCID 89874548—
ProductHCID 89875005HCID 8987500560%

Reaction Steps

The title compound is prepared in 60% yield (31 mg, white solid) from methyl 3-(bromomethyl)-2-chloroisonicotinate (38 mg, 0.14 mmol) and (6-(2,2,2-trifluoroethoxy)pyridin-2-yl)methanamine hydrochloride (35 mg, 0.14 mmol, Amine-19) in a similar manner to Intermediate-2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09187475B2
Source datasetuspto-grants-2015_11
ORD IDord-b6a14bb7ce3342d6b4cbf197ebfd3e1b
Source noteuspto-grants-2015_11