Hydrochloric Acid → HCID 89875345, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of N-(2-((6-(2,2-difluoroethoxy)-5-methylpyridin-3-yl)methyl)-1-oxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-4-yl)acetamide (200 mg, 0.54 mmol, Step-1) in THF (5.0 mL) is added aqueous hydrochloric acid (3.0 mL) at rt. The reaction mixture is stirred at 90° C. for 16 hours. The reaction mixture is concentrated to give 220 mg (>99% yield) of the title compound as pale yellow solid.

Provenance & Evidence