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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 715256Generated: October 31, 2026

620608-63-1 → HCID 89874423, compound

https://huagongshe.com/reaction/715256

Reaction equation

Participants

RoleNameHCIDCharge
Reactant620608-63-1HCID 16786006—
ReactantEthyl 3-(bromomethyl)-2-chloroisonicotinateHCID 89874240—
ProductHCID 89874423HCID 8987442354%

Reaction Steps

The title compound is prepared in 54% yield (130 mg, white solid) from ethyl 3-(bromomethyl)-2-chloroisonicotinate (180 mg, 0.64 mmol, Step-1 of Intermediate-1) and (6-(4-fluorophenoxy)pyridin-3-yl)methanamine (140 mg, 0.64 mmol, Amine-18) in a similar manner to Intermediate-2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09187475B2
Source datasetuspto-grants-2015_11
ORD IDord-1e29dc74909747b8ac68d225cef88c63
Source noteuspto-grants-2015_11