HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3,3-Trifluoro-1-propanol → HCID 66802967, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3,3-Trifluoro-1-propanol | HCID 137512 | — |
| Reactant | Methyl 6-chloropyridine-3-carboxylate | HCID 254249 | — |
| Product | HCID 66802967 | HCID 66802967 | 47% |
Reaction Steps
The title compound is prepared in 47% yield (1.37 g, colorless oil) from methyl 6-chloronicotinate (2.0 g, 11.7 mmol) and 3,3,3-trifluoropropan-1-ol instead of 2,2,2-trifluoroethanol in a similar manner to Step-3 of Amine-9.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187475B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-fb0fa8773f5f453aa71fe1c8b7e0d2c7 |
| Source note | uspto-grants-2015_11 |