HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3,3-Trifluoro-1-propanol → HCID 82956186, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3,3-Trifluoro-1-propanol | HCID 137512 | — |
| Reactant | 5,6-Dichloronicotinic acid | HCID 247987 | — |
| Product | HCID 82956186 | HCID 82956186 | 66% |
Reaction Steps
The title compound is prepared in 66% yield (6.48 g, white solid) from 5,6-dichloronicotinic acid (7.00 g, 36.5 mmol) and 3,3,3-trifluoropropan-1-ol (8.32 g, 72.9 mmol) in a similar manner to Step-1 of Amine-1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187475B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-47f52eeb4c1548dbb4b64c2e5877e7b4 |
| Source note | uspto-grants-2015_11 |