Dodecylamine → HCID 89874685, compound

HRID 715474Notes

Reaction equation

HRID 715474 reaction equation
[F:1][C:2]([F:25])([CH3:24])[CH2:3][O:4][C:5]1[N:10]=[CH:9][C:8]([CH2:11][N:12]2C(=O)C3C(=CC=CC=3)C2=O)=[CH:7][C:6]=1[CH3:23].CCCCCCCCCCCCN>>[F:25][C:2]([F:1])([CH3:24])[CH2:3][O:4][C:5]1[N:10]=[CH:9][C:8]([CH2:11][NH2:12])=[CH:7][C:6]=1[CH3:23]

Participants

3

Reactant 2

HCID 13583DodecylamineHCID 89875507HCID 89875507, compound

Product 1

HCID 89874685HCID 89874685, compoundYield 95%

Procedure

The title compound is prepared in 95% yield (699 mg, colorless oil) from 2-((6-(2,2-difluoropropoxy)-5-methylpyridin-3-yl)methyl)isoindoline-1,3-dione (1.18 g, 3.41 mmol) in a similar manner to Step-5 of Amine-12.

Sources & evidence

ORD record
ord-649d4235ae184421be03cf40b33614a9
Source dataset
uspto-grants-2015_11
Patent number
US09187475B2

Reaction notes

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