Dodecylamine → HCID 89874508, compound

HRID 715477Notes

Reaction equation

HRID 715477 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH2:14][N:15]2C(=O)C3C(=CC=CC=3)C2=O)[CH:5]=[N:6][C:7]=1[O:8][CH2:9][C:10]([F:13])([F:12])[CH3:11].CCCCCCCCCCCCN>>[Cl:1][C:2]1[CH:3]=[C:4]([CH2:14][NH2:15])[CH:5]=[N:6][C:7]=1[O:8][CH2:9][C:10]([F:12])([F:13])[CH3:11]

Participants

3

Reactant 2

HCID 13583DodecylamineHCID 89874623HCID 89874623, compound

Product 1

HCID 89874508HCID 89874508, compoundYield 96%

Procedure

The title compound is prepared in 96% yield (734 mg, colorless oil) from 2-((5-chloro-6-(2,2-difluoropropoxy)pyridin-3-yl)methyl)isoindoline-1,3-dione (1.18 g, 3.22 mmol, Step-2) in a similar manner to Step-5 of Amine-12.

Sources & evidence

ORD record
ord-63c1db1720544551a0a9f9815e797730
Source dataset
uspto-grants-2015_11
Patent number
US09187475B2

Reaction notes

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