HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 118037353, compound → HCID 20735409, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 118037353 | HCID 118037353 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 20735409 | HCID 20735409 | — |
Reaction Steps
Benzyl 4-(isopropylcarbamoyloxy)piperidine-1-carboxylate (113 mg) is dissolved in ethanol (3 mL), treated with palladium on carbon (10%, 38 mg) and the mixture is hydrogenated at room temperature for 8 hours under 3 bar hydrogen pressure. Then the catalyst is filtered off and washed with ethanol. The combined mother liquours are concentrated to give the title compound, which is used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09187477B2 |
| Source dataset | uspto-grants-2015_11 |
| ORD ID | ord-54beba9a5a8a4a26bf7bdacda2fdf46b |
| Source note | uspto-grants-2015_11 |