Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 86701046 | HCID 86701046 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86701048 | HCID 86701048 | — |
Reaction Steps
To 10 ml of dry methanol saturated with ammonia was added 0.5 mmol of ethyl 2-((3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)butanoate. The pressure tube was stoppered tightly, and the solution was stirred for 16 hours at 50° C. The white precipitate was collected and washed with cold methanol to give 2-((3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)butanamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09187484B2 |
|---|
| Source dataset | uspto-grants-2015_11 |
|---|
| ORD ID | ord-af9e65e38fac424782ad5aa9a112d1ce |
|---|
| Source note | uspto-grants-2015_11 |
|---|
