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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 716787Generated: October 30, 2026

1-Oxaspiro(2.4)heptane → 3-Hydroxy-3-(3-((1-hydroxycyclopentyl)methylamino)phenyl)propanenitrile

https://huagongshe.com/reaction/716787

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Oxaspiro(2.4)heptaneHCID 637991—
Reactant3-(3-Aminophenyl)-3-hydroxypropanenitrileHCID 59316960—
Product3-Hydroxy-3-(3-((1-hydroxycyclopentyl)methylamino)phenyl)propanenitrileHCID 67296710—

Reaction Steps

Reaction between 1-oxaspiro[2.4]heptane and aniline 12 gives 3-hydroxy-3-(3-((1-hydroxycyclopentyl)methylamino)phenyl)propanenitrile.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09193669B2
Source datasetuspto-grants-2015_11
ORD IDord-78983b14ab8c4670b6aa5c63a45d1f64
Source noteuspto-grants-2015_11