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HRID717226

反应详情

EQUATION

反应方程式

HRID 717226 的结构方程式

REACTANTS

反应物

3
结构：O=P(Cl)(Cl)Cl
HCID24813

Phosphoric trichloride

Cl3OP

结构：NNC(N)=S
HCID2723789

Thiosemicarbazide

CH5N3S

结构：O=C(O)C1(C(F)(F)F)CCC1
HCID2782838

1-(Trifluoromethyl)cyclobutanecarboxylic acid

C6H7F3O2

PRODUCTS

生成物

1
结构：Nc1nnc(C2(C(F)(F)F)CCC2)s1
HCID67545793

5-[1-(Trifluoromethyl)cyclobutyl]-1,3,4-thiadiazol-2-amine

C7H8F3N3S

PROCEDURE

实验过程

Commercially available, 1-(trifluoromethyl)cyclobutanecarboxylic acid (Oakwood), thiosemicarbazide (Aldrich) and phosphorus oxychloride (Aldrich) were processed as described for Example 1A to obtain the title compound. MS (ESI+) m/z 224 (M+H)+.