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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 717838Generated: November 3, 2026

Hydrochloric Acid → HCID 66992779, compound

https://huagongshe.com/reaction/717838

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,4-DioxaneHCID 31275—
ReactantHCID 58515955HCID 58515955—
ProductHCID 66992779HCID 66992779199.1%

Reaction Steps

tert-Butyl 4-(6-acetyl-8-chloroimidazo[1,5-a]pyridin-5-yl)piperazine-1-carboxylate (19 mg, 0.051 mmol) was taken into a vial and 4.0 M hydrogen chloride in 1,4-dioxane (1.0 mL, 4.0 mmol) was added and was stirred for 15 minutes. The solvents were evaporated to give the desired compound (16 mg, quantitative). LCMS calculated for C13H16ClN4O (M+H)+: m/z=279.1. found: 278.9.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09193721B2
Source datasetuspto-grants-2015_11
ORD IDord-cb25477e57dc449fa430bff5a9eb21a4
Source noteuspto-grants-2015_11