Perchloric Acid → O-(2,4,6-Trimethylbenzenesulfonyl)hydroxylamine

참여 물질

반응 단계

The ethyl (1Z)—N-[(mesitylsulfonyl)oxy]ethanimidoate (5.0 g, 18 mmol) was dissolved in 1,4-dioxane (4.5 mL, 58 mmol) and cooled in an ice bath under nitrogen. Perchloric acid (2.3 mL, 38 mmol) was added drop wise over 3 minutes. The reaction slowly became a thick mixture after 20 minutes. Ice (50 mL) was added to the reaction. The reaction was extracted with ethyl ether. The combined organic layer was washed with brine, dried over potassium carbonate (solid) and the volume was reduced to about 40 mL. LCMS calculated for C9H14NO3S (M+H)+: m/z=216.0. found: 215.9.

출처 및 근거