HCID 3419205, compound → HCID 20116191, compound

HRID 717907Notes

Reaction equation

HRID 717907 reaction equation
[CH2:1]([NH:6][C:7](=[O:17])[C:8]1[CH:13]=[CH:12][C:11]([N+:14]([O-])=O)=[CH:10][CH:9]=1)[CH2:2][CH:3]([CH3:5])[CH3:4].[H][H]>[Pd].CO>[NH2:14][C:11]1[CH:10]=[CH:9][C:8]([C:7]([NH:6][CH2:1][CH2:2][CH:3]([CH3:4])[CH3:5])=[O:17])=[CH:13][CH:12]=1

Participants

5

Reactant 2

HCID 3419205HCID 3419205, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 20116191HCID 20116191, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

N-Isopentyl-4-nitrobenzamide (1 g, 4.23 mmol) and methanol (40 ml) were added to palladium on carbon (0.200 g, 1.879 mmol) in a 250 mL SS pressure bottle and the mixture was stirred for 6 hours with hydrogen at 30 psi and room temperature. The mixture was filtered through a nylon membrane and concentrated to provide the title compound.

Workup

  1. filtrationThe mixture was filtered through a nylon membrane
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-d1d53e772a1b4f40b98c3fa453dd293e
Source dataset
uspto-grants-2015_11
Patent number
US09193723B2

Reaction notes

Loading…